male contraceptives

Hey, Figleaf's Dream Already a Reality? ContraVac Offers SpermCheck Male Fertility and Contraception-Effectiveness Test Kits

Thu, 2011-07-28 14:07

Speaking of easily-administered tests for a male contraceptive effectiveness, according to NewsMedical.net

SpermCheck Contraception, is now undergoing testing in a multi-center, NIH-funded study that is evaluating the effectiveness of a new contraceptive drug for men. Once a man starts using one of the current experimental male contraceptives, which are based on steroid compounds, sperm counts decline over a period of several months. The SpermCheck Contraception device could serve as a companion product to help men determine when sperm counts have reached safe levels should a male contraceptive drug or device become available in the marketplace.

Source:

At least one company already manufactures a home-test product, SpermCheck Fertility, for checking general male infertility and another for confirming sterility after a vasectomy.

As I've said over and over, this kind of antibody-tagging test is pretty great. And while at least initially the price tag will be way too high (their current kits cost about $34 each from Amazon) one would expect that higher volume and/or market competition from other brands could drive the price down to a point where they could be used for spot checks.

I expect most people imagine the main use would be before an episode of "causal" sex. Although really, for casual sex any contraceptive should be used to backup the condom everyone really, really should be using. (And if the price ever came down enough it actually might be nice if they could be inexpensively sold in condom machines.)

But in practice, since like a lot of hormonal contraceptives for women there's a lag begin when you begin using it and when it starts working I think the more useful application for a spot check for male contraception would be to see if it's started working. Or, towards the end of the effectiveness cycle, to know when it's no longer working.

Anyway, good do see some version of my fantasy male-fertility test is already on the market and that tests that even more closely target male contraception is in the works.

The Pill for Men, the Pill for Women: Why Would it Have to Be an Either/Or Choice? Plus, the Beneficial Impact on Men

Mon, 2011-07-25 15:51

Courtney Martin asks of the recent and trending buzz about effective hormonal contraception for men

...if you’re the kind of gal who partners with men, would you trust them to take oral contraception responsibly or would you rather keep the pill in your court, so to speak?

Source: Feministing

All things considered wouldn’t it be better if you both kept the pill in your respective courts?

Because while even the low-dose versions of The Pill for women are quite reliable when taken conscientiously in practice the risks of fertility can be higher. It does sound like most of the mechanisms for hormonally deactivating sperm or blocking its production (testosterone, progestin) might create a little more room for slackers. But while there’s no reason believe men would be any less reliable than women about taking The Pill for men, there’s also no reason to believe they’d be any more so.

There’s a reason reasonably cautious people always rely on two forms of contraception. And the advent of a male Pill isn’t going to magically change that.

What it will change is that it’ll give men a third contraceptive option beyond condoms and vasectomies. And since it’ll almost certainly be more reliable than condoms for contraception, and waaaay more reversible than vasectomies, I’m guessing the uptake will actually turn out to be pretty high.

Martin also semi-snarks

"Of course, women may have to trust that their partners are using birth control, as men do now. But at least one method, hormone implants, visibly bulge from a man’s bicep. 'Guys like it because they can show it off,' Dr. Amory said. 'Proof that the male is contracepting.'

I can already hear the craptastic pick-up lines. Lordy.

First of all, based at least on my experience with a vasectomy at age 21, while my partners tended to be interested that I had one I don’t believe knowing I was infertile changed anyone’s decision one way or the other. So while there may be some bicep-flexers trying to show off I’m pretty sure that's never going to be anyone's deciding factor for hookups.

One thing I think will be really important about a male Pill, is a verification method to make sure it’s working. Comic imagery not withstanding, a chip in a bicep would be good. Even better though would be one that could be checked on the spot pregnancy-test style with, say, tagged-antibodies for active presence of either active or inactive sperm in semen or pre-ejaculatory secretions. (Extra credit if saliva or urine could be used instead.)

Anyway, not only would something like that be useful confirmation for women in couples who are just initiating sex with each other, it would be useful for men to confirm that their contraceptive is working correctly.

And finally, I feel quite confident that when a reliable but easily reversible form of non-barrier contraception becomes available for men that it’ll transform men’s relationship with our fertility, it will reduce our odd indoctrinated fatalism about pregnancy being “in the woman’s hands,” and it’ll definitely reduce peer male sympathy when another man’s partner has an unplanned, unwanted pregnancy.

I’ve mentioned this before elsewhere but I think for once MRA-style paranoia about “paternity fraud” and forms of pregnancy-related learned helplessness can be used to increase demand for a male Pill! Although even then over time I suspect having more pragmatic control over their own fertility will tend to mellow a lot of those guys out and/or make it more difficult for them to play the victim card if they choose to avoid it.

Quick question for Martin: would it be so snarky if the bicep flexers were showing off not to potential hookups but to other men who hadn't yet gotten theirs?

With Paternity Revision Comes Great Paternity Responsibility -- Good Thing New Male Contraceptives Are Finally On the Horizon

Tue, 2011-02-22 23:42

The need to adjust our pre-feminist notions of paternal responsibility notwithstanding, this unpublished draft from last December is a reminder that we need to adjust pre-HIV notions of "sexual freedom" in relationship to condom use.  (The context was the Julian Assange incident.)

Anthony McCarthy of Echidne of the Snakes, who remembers the impact HIV had on his community of gay men, brings his bitter understanding of condom-avoiding "knowing transmission" to heterosexuality.

...as you know, women are infected with HIV through vaginal sex as well as through anal sex by men who are infected. Straight men are often infected through anonymous sex with women or men just as gay men are. I suspect that for many women, who have grown up with the idea that AIDS is primary a problem for gay men are at the stage gay men were in the early days before the syndrome even had a name.

Of course this is all by way of explanation for my comments on the accusations made about Julian Assange. Being a witness to the deaths of dozens of gay men I knew, knowing that just about all of them with a few exceptions, likely were infected through casual sex with someone they didn't know, knowing that women can be infected by men, all of that informs my thinking on whether or not people should be having casual sex with people they don't know in 2011. And the fact is they shouldn't. Women deserve better than they're going to get from men under those circumstances, men who have sex with men deserve better than they get from it. There is nothing liberated about being infected with HIV or hepatitis or chlamydia or any number of other infections that can injure and kill you. Having sex with someone who can persuade you to engage in sex you don't want or who can trick or force you into it is the opposite of free choice. No more than getting robbed by a conman. And there is no law you can make that will protect you from any of that which is stronger than protecting yourself. And there is nothing that is more likely to protect you than knowing who it is you're agreeing to have sex with.

Source: Echidne of the Snakes

At the time I drafted this I was on a real tear about "knowing transmission" not only of sexually transmitted diseases but pregnancy.  The more diligently men pursue reproductive responsibility the easier, both socially and biologically, it'll be to advocate for revision of paternity statutes as well.

(Good news on the paternal contraception front, incidentally.  Via Beth Saunders, it sounds like in addition to condoms, withdrawal, and/or surgical sterilization men will soon have not one but three reversible hormonal contraceptives to pick from, which means that men will finally be able to use double contraception without help from a partner.)

Will we ever be able to ditch condoms? Not as long as there continue to be multiple partners and sexually-transmittable illnesses. But with the possibility of new male contraceptives we can dramatically reduce the possibility of knowingly or even just carelessly transmitting paternity.

UK Researchers Looking for Pregnancy-Test Style On the Spot Detection of Sexually Transmitted Diseases

Wed, 2010-11-10 12:06

Speaking of the intersection of technology, STIs, contraception,

Jennifer Welsh of Discover Magazine’s Discoblog says UK researchers are working on inexpensive, disposable pee-on-a-stick type tests for sexually transmitted diseases. She says they’d be used in combination with cell phones (presumably to transmit results for analysis?)

Diagnostic sticks for chlamydia, gonorrhea, and herpes are estimated to cost a little over a dollar, and could be sold in pharmacies and vending machines in night clubs. A worried person would take the test by peeing or spitting on the computer chip-enabled diagnostic stick, connecting it to their phone or computer, and would get the results in minutes. (This microfluidic device sounds similar to other “lab-on-a-chip” devices under development.) The mobile or computer app could also recommend doctors.

Source: Discover Blogs

This is pretty cool. As with a lot of immediate-situation testing the key will be the rate of false negatives — situations where the test fails to detect existing disease. False positive STI tests are obviously annoying but nowhere as consequential(!!!) in the long run.

Along the same lines, as I’ve mentioned elsewhere, when hormonal contraception for men becomes available I think it would be very good if on-the-spot confirmation of effectiveness was available as well. It would be very nice if the proposed pee-on-a-stick sort of testing for STIs can be extended to include that.

Condoms Are to Male Contraception as City Buses Are to Public Transportation: Not Good Indicators of Overall Acceptance

Sun, 2010-08-08 12:35

In replying to a perfectly reasonable comment by on my post about male contraceptive pills I had a little epiphany about condoms.

The short version of a very common question would be: men tend to be reluctant to use condoms so why assume they’d be more willing to use a pill instead?

It occurred to me that, for whatever reason, for both men and a lot of women, condoms seem to be to contraception what city buses are to public transportation: sensible, practical, economical, reliable, and… underused and underappreciated compared to, say, subways or single-occupancy vehicles. In other words it’s inexplicably dumb but, for condoms and buses both, shouldn’t be taken as evidence of universal hostility to their respective ideas.

68,000 out of 100,000 AskMen Readers Would Use Male Birth Control Pills

Sat, 2010-08-07 08:53

Em & Lo report that according to an AskMen.com survey with close to 100,000 responses…

If a male birth control pill became available, 68% of men would take it.

Read the quote in context here.

There are usually dozens to hundreds of reasons to dismiss the credibility of online surveys, not least surveys conducted by the likes of AskMen and it’s sister publication Cosmopolitan. And even more reason to be leery of the results given that neither the publishers nor the readers AskMen or Cosmo are particularly highly placed on the progressive/feminist enlightenment scale.

In this case, for this answer on this survey, I think that’s actually a bonus rather than a liability. Because if 68% of self-selected AskMen readers in the 18-30 age demographic say they’d take a male birth control pill that’s…

Well, that’s just incredibly encouraging.

Ordinarily that’s precisely the demographic skeptics point to while claiming that R&D on male contraceptives is a waste of time.

With almost no encouragement whatsoever (least of all encouragement from either AskMen or Cosmo!) roughly 68,000 out of 100,000 nominally callow youths said yes they would. Imagine how many more would say yes with even a modicum of marketing.

Pill Use Down, Tubal Ligation Up in the U.S. Relative to UK, Netherlands, France

Fri, 2010-05-28 12:23

In a news roundup Katy of Jezebel passes along news about contraception in the U.S.

Out of married U.S. women, only 16% are currently on the pill, compared to 29% in the UK and more than 40% in the Netherlands and France. Surprisingly, sterilization is a much more popular option in America.

1 in 4 married ladies here have had their tubes tied, while most other countries that reported figures have sterilization rates below 10%. These patterns also appear to apply to all women – not just the ones who have tied the knot.

She said it here.

Statistics for contraceptive use by men is surprisingly sketchy — since virtually all the focus around contraception and pregnancy is on women, including focus on statistics-gathering, virtually all information about men and contraception has to be extrapolated from assumptions that women who use contraceptives tend to have male partners. Oh, and I say “surprisingly” because men still have direct access over three kinds of contraception: condoms, withdrawal, and vasectomies, with the most recently invented (vasectomies) still being nearly 200 years old! So how long would that questionnaire be anyway? But I digress…

The best… or at least most frequently-cited estimate for male sterilization in the U.S. is one in six men over age 35 or, I think, a little more than 15%.

Fade to Numb on Fading to Zero Sperm Count

Thu, 2009-03-26 10:52

You know that little statistic about the first-year reliability rate for vasectomies is 99% instead 100%? Fade to Numb, who had a vasectomy about three months ago, has an important public service announcement that’s strongly related to that.

In the meeting with the doctor at the time, as well as from the papers I brought home afterwards, I learned something interesting. Evidently, no more than half of the guys that get vasectomies actually go back into the lab at a later date to make sure their specimen is all clear. (“Specimen is all clear” could be translated as “all the little spermies are completely gone from the semen system.”)

And (surprise surprise) it can take many months and upwards of 20 ejaculations before they all get cleared out. So some of those people that have “miracle children” after vasectomies? I suspect some of them are less “miracle” and more “didn’t bother to follow up after an operation.”

...

Long story short (or, rather, less long), I got a letter back from the doctor the next week. Sadly, it stated that I’ve still got some sperm swimming around in the system, and I need to take another specimen back to the lab in another three months, and until that time I need to make sure I use proper protection during sex.

Read the quote in context here.

Point being that vasectomies actually are extremely good for keeping new sperm cells out of semen. But you’re not sterile till the last of the old cells are out of your system.

For the record there’s a very, very small chance that his vasectomy really didn’t work and that sperm is somehow getting past the snips. If so then his follow-up check will detect that and he and his partner can decide what to do next. meanwhile, though, they’re not going to make assumptions about whether he is or isn’t still fertile.

Cool post.

Trust But Verify

Mon, 2009-02-16 23:51

In an excellent rundown of current male-contraceptive technology in development, Soumya Vemuganti of RHRealityCheck.org says a product I’ve been waiting for for years has been approved by the FDA last year.

Confirming Lack of Sperm Production 

Since it takes just one sperm to fertilize an egg, it is extremely important to confirm a lack of sperm production using any of the aforementioned male contraceptives.   A product approved by the FDA last year will help to measure the effectiveness of male contraceptives which block spermatogenesis.  SpermCheck Vasectomy offers patients an at home method of measuring their sperm levels post-vasectomy.  It is easy to imagine that this product could also be used to measure the efficacy of reversible male contraceptives; in fact, SpermCheck Contraception is in the works. 

Read the quote in context here.

Because non-barrier/non-vasectomy contraception for men is almost always going to be a lot more complicated than the main non-barrier/non-IUD contraceptives for women having a method to confirm one’s infertility seems pretty critical. And, obviously, it’s just as critical to be able to confirm one’s male partner’s infertility as well. I’m guessing that at least initially the test won’t be cheap enough for casual use — the size of a market based on one-time-only post-vasectomy tests can’t be terribly high — on the order of several hundred thousand a year — and they’ve gotta recover their costs somehow. Presumably with the advent of oral/injectable contraceptives or, possibly more exciting, hotpack-based methods (who knew? but they say it can be 100% effective!) the market could grow into the tens of millions of repeat customers. Presumably that would make the product affordable for frequent use.

One of the few things generally applicable things Ronald Reagan said (over, and over, and over… he was already developing Alzheimer’s) during his negotiations with Mikhail Gorbachev was “trust but verify.” Which seems like a tailor-made tagline for a fertility testing product.

HNT - Vasectomy Week?

Wed, 2008-12-10 18:13

FTN of Fade to Numb just had one. Kidder at Sex is Fun has (duh, medical not erotic but still not work safe) photos of his. Em and Lo interviewed a younger (27-year-old) about why he got his (it’s a long list.)

And late last week I gave a friend a ride home from the clinic after he had his.

It’s been a while but I’ve had two (one at age 21, another at 44, with a reversal in between) but this just seemed like a good week to break out my two vasectomy-related mementos. The ring I cast from silver and gold in my college metal-arts shop. The license plate I picked up at a yard sale recently (the seller’s partner had given him a vasectomy shower years before when he got his.)

Happy HNT (or Half-nekkid Thursday!)




More like this here.

User login